久坐不动行为和体力活动与睡眠持续时间和睡眠质量的纵向关联,在患有结肠直肠癌和结肠直肠癌以外的人群中
Koen G Frenken1, Laurien M Buffart2, Martijn Bours1
1Department of Epidemiology, GROW Research Institute for Oncology and Reproduction, Maastricht University, Maastricht, the Netherlands.
Cancer control : journal of the Moffitt Cancer Center
|November 14, 2025
概括
久坐不动的行为和体力活动对结直肠癌 (CRC) 幸存者的睡眠产生影响. 更多的站立可能会改善睡眠质量并减少失眠,而更多的活动与更短的睡眠时间有关.
科学领域:
- 在瘤学瘤学.
- 睡眠医学 睡眠医学
- 行为科学 行为科学
背景情况:
- 在结直肠癌 (CRC) 幸存者中,睡眠质量差和睡眠障碍很普遍.
- 静坐行为,站立和体力活动对这一群体睡眠结果的具体影响尚不清楚.
- 了解这些关系对于开发有针对性的干预措施来改善幸存者护理至关重要.
研究的目的:
- 检查静坐行为,站立和身体活动与CRC幸存者的睡眠时间和质量之间的纵向关联.
- 在治疗后五年内调查这些关联.
- 提供对可修改的生活方式因素的见解,这些因素会影响癌症幸存者的睡眠.
主要方法:
- 一项前性队列研究,涉及401名I-III阶段CRC的幸存者.
- 客观测量静坐时间,站立时间和身体活动,使用大腿佩戴的加速度计.
- 通过自我报告问卷和60个月治疗后客观措施评估睡眠时间,变化,质量和失眠症状.
- 使用混调整的线性混合模型分析了纵向关联.
主要成果:
- 增加的久坐行为与睡眠时间缩短有关.
- 增加站立时间与更短的睡眠时间,更高的睡眠可变性,更好的睡眠质量和减少失眠症状有关.
- 较高的总体体力活动与睡眠时间缩短和睡眠变化增加有关,而中度至强度的体力活动与睡眠时间缩短和失眠症状减少相关.
结论:
- 身体活动水平和站立行为与结直肠癌幸存者的睡眠相关症状有显著的关联.
- 用站立和/或体力活动代替久坐行为可能是缓解睡眠障碍的可行策略.
- 需要进一步的研究来证实这些生活方式修改对改善CRC幸存者的睡眠结果的有效性.
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