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新失焦眼镜镜片对近视控制的一年有效性:一项随机临床试验
Xiaotong Han1, Yurui Zhang1, Ling Jin1
1State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangzhou, Guangdong, China.
Ophthalmology science
|November 14, 2025
概括
新型失焦眼镜镜 (MYOGEN) 在1年的时间里,与单视镜 (SVL) 相比,在儿童中显著降低了近视的进展和轴延长.
科学领域:
- 眼科医生 眼科 眼科
- 儿科光学测量 儿科光学测量
- 控制近视 控制近视
背景情况:
- 近视的进展是全世界儿童日益关注的问题.
- 传统的单视镜头 (SVL) 不能有效地减缓近视的进展.
- 新的眼镜镜片设计旨在解决这一未得到满足的临床需求.
研究的目的:
- 评估新型失焦眼镜镜片 (MYOGEN) 在预防近视进展方面的有效性和安全性.
- 为了比较MYOGEN与SVL对儿童折射误差和轴长度的影响.
主要方法:
- 进行了一项随机的,开放的,受控的临床试验.
- 6-14岁的近视儿童被录取并随机分配给接受MYOGEN或SVL.
- 主要结果是球体等效折射 (SER) 的1年变化;轴长 (AL) 是一个关键的次要结果.
主要成果:
- 与SVL相比,MYOGEN在1年后显著降低了近视进展 (SER变化: -0.80 D与 -1.06 D) 和轴延长 (AL变化:0.25 mm与0.37 mm) (P < 0.001).与SVL相比,在1年后显著降低了近视进展 (SER变化: -0.80 D与 -1.06 D) 和轴延长 (AL变化:0.25 mm与0.37 mm).
- 治疗效果在符合治疗要求的患者 (≥8小时/天) 中更为明显.
- 两组之间没有观察到视觉质量或眼镜佩戴合规性的显著差异.
结论:
- 新型失焦眼镜镜片 (MYOGEN) 在1年时间内有效减少近视的进展和儿童的轴延长.
- 在儿童群体中,MYOGEN为SVL提供了一个有前途的替代方案,用于治疗近视.
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