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急性非引起的肺栓塞是未被诊断的宏壮病的第一个表现
Saad Muhammad1, Aly Barakat1, Annzel Jais1
1Department of Cardiology, Medway NHS Foundation Trust, Gillingham, GBR.
Cureus
|November 14, 2025
概括
巨症是一种导致生长激素过量的疾病,可导致高凝血和静脉血栓栓塞. 这一案例突出了一个患者被诊断出患有肺栓塞后的壮症.
科学领域:
- 内分泌学 在内分泌学.
- 心脏病学 心脏病学
- 在瘤学瘤学.
背景情况:
- 巨症的特征是生长激素的过度产生,与高凝血能力的风险增加有关.
- 未被诊断的壮症可能伴有静脉血栓栓塞 (VTE),如肺栓塞 (PE).
- 识别VTE的潜在原因对于适当的患者管理至关重要.
研究的目的:
- 报告一个呈现为急性双边肺栓塞的壮病病例.
- 强调在无法解释的VTE患者中考虑壮症的重要性.
- 为了说明一个患有VTE的患者巨病的诊断工作.
主要方法:
- 一个50多岁的男性患者的病例报告显示,他患有肺炎性胸痛和呼吸短促.
- 诊断调查包括PE的计算机断层扫描肺血管造影 (CTPA),恶性瘤的CT成像和内分泌评估.
- 内分泌评估包括测量胰岛素样生长因子-1 (IGF-1) 和进行口服葡萄糖耐受性测试 (OGTT).
主要成果:
- CTPA证实了急性双边肺栓塞.
- 没有发现恶性瘤或VTE的明显诱导因素.
- 升高的IGF-1和阳性OGTT证实了壮症,归因于垂体腺瘤.
结论:
- 这一案例强调了壮症和高凝血能力之间的潜在联系,导致VTE.
- 在患有不明原因的VTE的患者中,早期识别缩症至关重要.
- 综合性评估,包括内分泌评估,对于诊断壮病和管理相关风险至关重要.
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