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美国食道癌死亡率趋势:使用CDC WONDER数据的综合纵向研究 (1999-2023年)
Xuefei Yang1, Yinyan Shao2, Junhua Guo1
1Department of Oncology, Hangzhou TCM Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.
Frontiers in public health
|November 14, 2025
概括
自1999年以来,食道癌死亡率在美国总体上有所下降,但仍然存在显著的差异. 对非西班牙裔白人,农村地区和老年人需要有针对性的干预措施.
科学领域:
- 流行病学 流行病学
- 公共卫生 公共卫生
- 癌症研究 癌症研究
背景情况:
- 食道癌仍然是一个重大的全球健康问题.
- 了解人口水平的死亡率趋势对于公共卫生至关重要.
- 这项研究分析了1999-2023年美国食道癌死亡率.
研究的目的:
- 为了检查美国食道癌死亡率的趋势.
- 根据性别,种族,城市化,地区和年龄来确定死亡率的变化.
- 评估进步对人口水平死亡率的影响.
主要方法:
- 使用CDC WONDER数据库进行死亡率数据 (ICD-10代码C15.0-C15.9).
- 分析了年龄调整后的死亡率 (AAMR),使用结点回归.
- 按人口,地理和年龄组分层次化数据.
主要成果:
- 整体AAMR从每10万人口中的6.74降至5.61 (AAPC: -0.81).
- 在大多数群体中,死亡率下降,除非西班牙裔白人;非西班牙裔黑人死亡率下降最大 (AAPC: -4.07).
- 男性的发病率更高;大都会地区的发病率下降 (AAPC: -1.09),而非大都会地区的发病率上升 (AAPC: 0.48).
结论:
- 尽管总体下降,食道癌死亡率仍然存在显著差异.
- 在地理,城乡和年龄分组中发现的不平等.
- 针对弱势群体,包括非西班牙裔白人,农村居民和老年人,需要有针对性的干预措施.
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