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Updated: Jan 11, 2026

In Vivo Augmentation of Gut-Homing Regulatory T Cell Induction
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在炎症性肠病中利用抗原特异性CD4+调节性T细胞的机遇和挑战

Jessica Kümmel1, Nicolas Schlegel1, Johanna C Wagner1

  • 1Department of General, Visceral, Transplantation, Vascular and Pediatric Surgery, University Hospital Würzburg, Würzburg, Germany.

Frontiers in immunology
|November 14, 2025
PubMed
概括

化学抗原受体 (CAR) T细胞显示出治疗炎症性肠病 (IBD) 的前景. 基因工程调节T (Treg) 细胞为IBD患者恢复免疫平衡提供了一种新的治疗策略.

关键词:
一个CAR受体的受体.这就是IL23R-CAR.细胞治疗疗法细胞治疗疗法弗拉盖林 - 特定于CAR.免疫疗法 免疫疗法炎症性肠道疾病 炎症性肠道疾病监管性T细胞监管性T细胞

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