阿斯特拉加卢斯膜质提取物减少了功能性膝关节疼痛:一个随机,双盲,安慰剂控制的随机试验
Lorenzo Lippi1,2, Alessio Turco1, Girish H Rudrappa3
1Department of Health Sciences, University of Eastern Piedmont "A. Avogadro", Novara, Italy.
Frontiers in pain research (Lausanne, Switzerland)
|November 14, 2025
概括
阿斯特拉加勒斯膜根提取物 (AME) 在成年人中显著降低了膝盖疼痛和改善了关节功能. 这种食补充剂为管理膝关节疼痛提供了安全有效的替代方案.
科学领域:
- 综合医学是一个整体医学.
- 药理学 药理学是指药理学的学科.
- 临床营养学 临床营养学
背景情况:
- 人们越来越担心关节疼痛药物治疗的副作用,人们对食补充剂越来越感兴趣.
- 阿斯特拉加勒斯膜根提取物 (AME) 是作为一种潜在的天然疗法来缓解膝关节疼痛.
研究的目的:
- 评估用于功能性膝关节关节疼痛的标准化AME的疗效和安全性.
- 评估AME对减轻疼痛,关节功能和患者满意度的影响.
主要方法:
- 这是一项为期28天的双盲随机对照试验,涉及90名膝关节疼痛的成年人.
- 参与者接受了480毫克的AME或安慰剂,结果通过VAS,WOMAC,SCT和ROM进行评估.
主要成果:
- AME组显示膝关节疼痛显著减少30% (p < 0.0001),并且改善了WOMAC,SCT和ROM得分.
- 在AME组报告了更高的患者满意度,没有观察到严重的不良事件.
结论:
- 标准化Astragalus membranaceus根提取物 (AME) 是治疗膝关节关节疼痛的安全有效选择.
- 需要进一步的长期研究来探索AME的持续益处.
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