在嗅觉裂阻塞的正鼻和鼻后嗅觉功能
J H Juratli1,2, C Huart3,4, V Hox3
1Smell and Taste Clinic, Department of Otorhinolaryngology, Technische Universität Dresden, Dresden, Germany.
Rhinology
|November 14, 2025
概括
呼吸道腺形上皮性哈马托马 (REAH) 比其他嗅觉裂阻塞更明显地损害了正鼻和鼻后嗅觉功能. 慢性鼻炎和嗅觉裂综合征也会影响气味,在耳鼻功能方面差异更为明显.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 嗅觉神经科学是一种神经科学.
- 鼻科 鼻科是指鼻科的专家.
背景情况:
- 嗅觉裂阻塞显著影响嗅觉功能.
- 研究的疾病包括嗅觉裂综合征,慢性鼻炎 (有或没有鼻) 和呼吸道腺状上皮瘤 (REAH).
研究的目的:
- 在患有各种嗅觉裂阻塞的患者中研究和比较正鼻和鼻后嗅觉功能.
- 确定REAH和慢性鼻炎对嗅觉通路的特定影响.
主要方法:
- 93名患有嗅觉裂阻塞的患者接受了鼻腔内镜检查,化学传感事件相关的潜在记录和放射性评估.
- 分别使用完整的嗅探棒测试和基于粉末的测试来评估正鼻和鼻后嗅觉功能.
主要成果:
- 与慢性鼻炎患者相比,患有REAH的患者表现出明显降低的鼻腔和鼻后嗅觉功能,而慢性鼻炎患者的嗅觉裂有息肉.
- 嗅觉裂综合征单独导致了比组合条件更高的正鼻分数,但后鼻功能没有显著差异.
- 同时出现的慢性鼻炎并没有显著改变REAH患者的嗅觉功能.
结论:
- REAH与更严重的嗅觉功能障碍有关,影响嗅觉粘膜,而不仅仅是简单的空气流干扰.
- 慢性鼻炎和嗅觉裂综合征之间对嗅觉功能的区别在正鼻比鼻后评估中更明显.
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