相关实验视频
Updated: Jan 11, 2026

06:08
A Novel Method: Super-selective Adrenal Venous Sampling
Published on: September 15, 2017
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[由于上腺髓激增而引起的异胎性ACTH综合征的侵袭性过程. 案例报告] 案例报告]
M V Kats1, A Y Lugovskaya1, I V Komerdus1
1Vladimirsky Moscow Regional Research Clinical Institute.
Terapevticheskii arkhiv
|November 14, 2025
概括
在上腺髓中发现了一种罕见的异位 adrenocorticotropic 激素 (ACTH) 过分分泌的病例. 这种上腺瘤引起了严重的症状,导致双边上腺切除术进行治疗.
科学领域:
- 内分泌学 在内分泌学.
- 在瘤学瘤学.
- 病理学 病理学 病理学
背景情况:
- 宫外 adrenocorticotropic 激素 (ACTH) 综合征可以出现模糊的症状,使得诊断具有挑战性.
- 上腺髓是ACTH分泌瘤的不寻常位置.
研究的目的:
- 描述一个来自上腺髓的异胎性ACTH过分分泌的独特临床病例.
- 要突出诊断挑战和管理这种罕见的条件.
主要方法:
- 临床病例的介绍.
- 生物化学分析包括激素水平和电解质.
- 电心电图 (ECG) 和心声回声图 (Echo-CG).
- 图像学研究 (尽管受患者病情限制).
- 上腺组织的免疫组织化学检查.
主要成果:
- 一名64岁的肥胖妇女出现了严重的低血,高血压,2型糖尿病,胀和肌肉衰弱.
- 确认了内源性皮质过高和升高的ACTH水平,但没有确定下垂体源.
- 由于患者的危急状况,进行了双边上腺切除术.
- 免疫组织化学揭示了上腺髓中的ACTH分泌细胞,证实了子宫外源.
结论:
- 这一案例强调了上腺髓作为ACTH产生瘤的罕见部位.
- 临床警内源性高皮质症至关重要,即使是异常呈现.
- 在异胎ACTH综合征的严重病例中,迅速的外科手术 (上腺切除术) 可以拯救生命.
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