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Updated: Jan 11, 2026

Residue-Specific Exchange of Proline by Proline Analogs in Fluorescent Proteins: How "Molecular Surgery" of the Backbone Affects Folding and Stability
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Residue-Specific Exchange of Proline by Proline Analogs in Fluorescent Proteins: How "Molecular Surgery" of the Backbone Affects Folding and Stability

Published on: February 3, 2022

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Pentafluorophosphato-Phenylalanine的遗传编码 提供PF5-蛋白质作为蛋白模拟物

Anna Magdalena Ambros1, Haocheng Qianzhu2, Markus Tiemann1

  • 1Department of Biology, Chemistry, Pharmacy, Institute of Pharmacy, Freie Universität Berlin, Königin-Luise-Str. 2+4, 14195, Berlin, Germany.

Angewandte Chemie (International ed. in English)
|November 14, 2025
PubMed
概括

科学家们通过基因编码一种新型的酸铁模仿物,五酸-二甲-氨 (PF5CF2Phe),并将其转化为蛋白质. 这一突破使得蛋白质酸化的精确功能研究成为可能,这是一个关键的翻译后修改.

关键词:
基因编码是基因编码.非正规的氨基酸是非正规的氨基酸.五化酸盐是五化酸盐中的一种.铁的模仿剂 铁的模仿剂蛋白质氨酸酸酶是一种蛋白质氨酸酸酶.

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