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Updated: Jan 11, 2026

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在急性肝衰竭患者中细胞吸收应用的可行性和安全性

Haselwanter Patrick1, Fairfield Seanna1, Reinhold Riva1

  • 1Department of Medicine III, Division of Gastroenterology and Hepatology, Intensive Care Unit 13H1, Medical University of Vienna, Vienna, Austria.

Liver international : official journal of the International Association for the Study of the Liver
|November 14, 2025
PubMed
概括

与连续脏替代疗法 (CRRT) 一起使用的细胞吸收疗法,通过减少胆红素和改善生存率,在急性肝衰竭 (ALF) 患者中显示出潜在的益处. 需要进一步的研究来证实其临床影响.

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Chronic liver disease significantly impacts drug metabolism due to alterations in hepatic blood flow and enzyme accessibility. This disruption affects the body's pharmacokinetics—the movement and processing of drugs within the system. Key enzymes crucial for metabolizing medications become less accessible, changing how drugs are processed and utilized. Furthermore, liver disease influences the synthesis of plasma proteins, such as albumin and globulins, which play critical roles in drug...
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