高近视症中的玻璃眼,类似玻璃眼和非玻璃眼光神经病变:两大洲研究
Jost B Jonas1,2,3,4,5,6, Mukharram M Bikbov7, Gyulli M Kazakbaeva7
1Rothschild Foundation Hospital, Paris, France.
Investigative ophthalmology & visual science
|November 14, 2025
概括
高度近视的眼睛显示了非光眼和类似于光眼的视神经病变的显著流行. 这些情况通常分别超过20%和10%,与轴长和光盘大小有关.
科学领域:
- 眼科医生 眼科 眼科
- 视神经病症研究 视神经病症研究
- 近视研究 近视研究
背景情况:
- 高近视是各种眼部病理的重要危险因素.
- 了解近视的视神经病发病率对于早期检测和管理至关重要.
研究的目的:
- 为了确定多种不同人群中高度近视的个体中眼性 (GON),类似眼性 (GLON) 和非眼性视觉神经病变 (NGON) 的患病率.
- 调查这些视神经病变与眼睛参数 (如轴长和光盘大小) 之间的联系.
主要方法:
- 来自俄罗斯,印度和中国进行的五项基于人口的大规模研究 (UEMS,UVOS,UCES,CIEMS,BES) 的数据分析.
- 包括40岁及以上的参与者,并专门针对非常老人和儿童的队列.
- 视觉神经病发病率的评估和与轴长度,状区域特征和视觉盘大小的相关性.
主要成果:
- 在高度近视眼中,NGON和GLON/GON的患病率很大,通常分别超过20%和10%.
- NGON与较长的轴长度和更宽的近视的巴巴皮拉里贝塔/马区域有关.
- GLON/GON显示了与更大的光盘尺寸和较小程度上更长的轴长度的关联.
结论:
- 高度近视的眼睛表现出相当大的NGON和GLON/GON的流行率.
- 这些视神经病变与眼睛的结构参数有明显的关联.
- 这两种情况的患病率随着轴长而非线性增加,在极端近视方面达到高水平.
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