相关实验视频

Updated: May 2, 2026

Utilizing 18F-FDG PET/CT Imaging and Quantitative Histology to Measure Dynamic Changes in the Glucose Metabolism in Mouse Models of Lung Cancer

Utilizing 18F-FDG PET/CT Imaging and Quantitative Histology to Measure Dynamic Changes in the Glucose Metabolism in Mouse Models of Lung Cancer

Published on: July 21, 2018

放射基因组学:通过非侵入性成像和基因组整合来改变肺癌护理

Faridoddin Shariaty¹, Vitalii Pavlov²

¹Peter the Great St. Petersburg Polytechnic University, Politekhnicheskaya Ulitsa, 29, St. Petersburg, Russia, 195251. Shariaty3@gmail.com.

Medical oncology (Northwood, London, England)

|November 14, 2025

概括

放射基因组学使用成像来非侵入性地描述非小细胞肺癌 (NSCLC) 的基因组特征. 临床使用仍然存在挑战,但它补充了活检,用于个性化肺癌护理.

科学领域:

放射基因组学是指放射基因组学.
医疗成像医学成像
计算病理学计算病理学

背景情况:

放射基因组学将CT和PET/CT扫描的定量成像特征与瘤基因组学相结合.
这种方法旨在非侵入性地表征非小细胞肺癌 (NSCLC).

研究的目的:

审查NSCLC目前的放射遗传学工作流程,从图像采集到建模.
突出临床应用,包括分类,风险分层,治疗选择和监测.
确定阻碍临床翻译的挑战,并提出解决方案.

主要方法:

综合当前放射遗传学工作流程:图像采集,细分,特征提取和建模.
重点是临床用例和潜在应用.
讨论未来发展的挑战和建议.

主要成果:

放射基因组学显示出对NSCLC的非侵入性分析有希望.
临床翻译受到非标准化管道,验证问题和解释性挑战的限制.
基因组负担 (TMB,ITH,CNA) 应该被视为关键的终点.

结论:

放射基因组学是活检的宝贵补充,而不是替代.
协调的协议,强大的验证和可解释的AI对于临床整合至关重要.
未来的影响依赖于以患者为中心的肺癌护理的多omics集成.

关键词:

人工智能的人工智能是人工智能.生物标志物生物标志物欧洲农业基金会 (EGFR) 是一个基金.肺癌是一种肺癌.在NSCLCLC中,我们可以看到.放射基因组学是指放射基因组学.无线电学 (Radiomics) 是一种无线电学.

更多相关视频

Author Spotlight: Advancements in Molecular Biomarker Testing for Non-Squamous Non-Small Cell Lung Cancer

Author Spotlight: Advancements in Molecular Biomarker Testing for Non-Squamous Non-Small Cell Lung Cancer

Published on: September 8, 2023

Detection of Targetable Alterations in Non-small Cell Lung Cancer using Next-generation Sequencing

Detection of Targetable Alterations in Non-small Cell Lung Cancer using Next-generation Sequencing

Published on: October 10, 2025

相关概念视频

Radiological Investigation III: Pulmonary Angiogram and PET Scan

Radiological Investigation III: Pulmonary Angiogram and PET Scan

Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...

Pharmacogenetics of Drug Targets: β₂-Adrenergic Receptors, Apo E, Thymidylate Synthase

Pharmacogenetics of Drug Targets: β₂-Adrenergic Receptors, Apo E, Thymidylate Synthase

Genetic polymorphisms in drug targets have emerged as critical determinants of interindividual variability in drug response and toxicity. Pharmacogenomic investigations increasingly focus on identifying these variations to personalize and optimize therapeutic interventions. A drug target may be a receptor, enzyme, or signaling protein involved in pharmacologic responses or disease-related pathways. While early pharmacogenetic studies focused primarily on drug metabolism, current research...