老年男性卡洛摄入量与医院获得的肺炎之间的关联:一个横截面研究
Jun He1, Boyang Wei1, Xue-Geng Hong2
1Department of Nutrition, The 960th Hospital of the PLA Joint Logistics Support Force, Jinan, 250031, People's Republic of China.
Aging clinical and experimental research
|November 14, 2025
概括
高龄住院患者饮食中含有较高的胡卜素摄入量,其在医院获得的肺炎 (HAP) 风险显著降低. 这种反向关系显示了剂量反应效应高达1273.7μg/天,此后益处停滞不前.
科学领域:
- 老年学是一门学科.
- 营养科学 营养科学
- 传染病流行病学 传染病流行病学
背景情况:
- 老年住院患者面临高风险的医院获得的肺炎 (HAP).
- 食中胡卜素对该种人群中HAP风险的具体影响尚不清楚.
研究的目的:
- 调查饮食中胡卜素摄入量与老年住院患者中HAP患病率之间的关联.
- 确定是否存在剂量反应关系,并确定任何有益效果的摄入门.
主要方法:
- 一项涉及165名80岁及以上患者的横截面研究.
- 饮食中的胡卜素摄入量使用72小时回忆和食物称量来量化.
- 统计分析包括多变量后勤回归,受限制的立方线和值分析.
主要成果:
- 适度摄入饮食中的胡卜素 (713.4-2101.4微克/天) 与摄入量最低的组相比,与HAP风险降低80%有关.
- 在胡卜素摄入量和HAP风险之间观察到非线性,反向的关联 (非线性P = 0.003).
- 在卡洛摄入量超过1273.7微克/天后,保护作用趋于平稳.
结论:
- 增加的食类胡卜素摄入量与老年住院患者的HAP患病率相反相关.
- 存在剂量反应关系,在摄入门为1273.7μg/天之前观察到显著的益处.
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