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Updated: Jul 7, 2026

Metabolic Characterization of Polarized M1 and M2 Bone Marrow-derived Macrophages Using Real-time Extracellular Flux Analysis
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Metabolic Characterization of Polarized M1 and M2 Bone Marrow-derived Macrophages Using Real-time Extracellular Flux Analysis

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福西酸E通过向PKM2四重化来缓解肝损伤,以促进巨细胞M2极化

Bingxin Wu1, Xuechun Yu1, Yanling Li1

  • 1State Key Laboratory of Traditional Chinese Medicine Syndrome, International Institute for Translational Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, 510006, China.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|November 14, 2025
PubMed
概括

福西化物E (FE) 激活酸激酶M2 (PKM2),重编程巨细胞以减少败血症引起的肝损伤. 这项研究揭示了FE的FE.

关键词:
福西化物E 的含量肝脏损伤 肝脏损伤是什么?酸激酶 M2 的使用.败血症是什么 败血症是什么

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Drug-Induced Senescence in Liver Cells Promotes M2 Macrophage Polarization: Implications for Tyrosine Kinase Inhibitor-Associated Hepatotoxicity09:32

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Liver Regeneration01:24

Liver Regeneration

The liver is an important organ in vertebrates that plays an essential role in metabolism. It is also responsible for storing and redistributing nutrients such as carbohydrates, fats, and vitamins in the body. Additionally, the liver releases bile salts which are critical for digesting food and eliminating toxic metabolites from the body.
Cells of Liver
The liver comprises four major types of cells— hepatocytes, stellate, Kupffer, and sinusoidal endothelial cells. The hepatocytes are large...