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Updated: Jan 11, 2026

Assessing Cardiac Reprogramming using High Content Imaging Analysis
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Assessing Cardiac Reprogramming using High Content Imaging Analysis

Published on: October 26, 2020

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阻止核受体 Nr4a3 解锁衰老屏障,促进直接的心脏重编程

Mengxin Liu1,2, Zhangyi Yu1,2, Zechun He1,2

  • 1Department of Cardiology, Zhongnan Hospital of Wuhan University, Medical Research Institute, Frontier Science Center for Immunology and Metabolism, Wuhan University, Wuhan 430071, China.

Science advances
|November 14, 2025
PubMed
概括

细胞衰老阻碍纤维细胞直接重新编程成心肌细胞进行心脏修复. 向 Nr4a3 增强了这一过程,改善了心肌梗塞后的心脏功能.

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