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Updated: Jan 11, 2026

Molecular Analysis of Endothelial-mesenchymal Transition Induced by Transforming Growth Factor-β Signaling
07:49

Molecular Analysis of Endothelial-mesenchymal Transition Induced by Transforming Growth Factor-β Signaling

Published on: August 3, 2018

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综合素αvβ8介导的TGF-β1激活调节了在TPO-RA取消后免疫血栓缺血的持续反应

Heng Mei1, Min Xu1, Jinhui Jin Shu1

  • 1Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Blood
|November 14, 2025
PubMed
概括

研究免疫性血小板缺血 (ITP),研究人员发现,整合素αvβ8途径激活TGF-β1,恢复免疫耐受性. 这一途径代表了一种有前途的治疗目标,用于ITP患者不响应当前治疗.

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Visualization and Quantification of TGFβ/BMP/SMAD Signaling under Different Fluid Shear Stress Conditions using Proximity-Ligation-Assay

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