在接受计算机断层扫描扫描的儿童中,器官剂量和终身可归因的癌症风险
Divya K Mohan1, Senthil Kumar M2, Venkata Sai P M3
1Department of Human Genetics, Sri Ramachandra Institute of Higher Education and Research (Deemed to be University), Porur, Chennai 600 116, Tamil Nadu, India.
Journal of medical imaging and radiation sciences
|November 14, 2025
概括
儿童CT扫描中的辐射暴露增加了癌症风险. 这项研究量化了儿科CT扫描器官剂量和终身可归因风险 (LAR),强调了辐射安全的必要性.
科学领域:
- 医学物理 医学物理
- 放射学 放射学是一门学科.
- 儿科瘤学 儿科瘤学
背景情况:
- 越来越多地使用医学成像,特别是计算机断层扫描 (CT),导致儿科患者辐射暴露的增加.
- 电图扫描为扫描场内的器官提供辐射剂量,可能会增加长期癌症风险.
研究的目的:
- 计算儿科患者接受各种CT扫描的器官剂量.
- 根据CT检查,估计南印度儿童癌症发病率的终身可归因风险 (LAR).
- 在儿科参与者中评估与整个腹部,泌尿图,胸部和大脑CT扫描相关的与辐射有关的癌症风险.
主要方法:
- 招募了100名儿科参与者,他们接受了不同的CT扫描,按年龄组 (0-18岁) 分类.
- 使用输入到VirtualDoseTM CT软件中的扫描参数计算器官剂量.
- 估计癌症发病率的LAR使用来自电离辐射生物效应IIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIII
主要成果:
- 在结肠,胃,膀,肝脏 (全腹CT);膀,结肠,生殖腺,乳房 (泌尿图CT);肺,乳房 (胸部CT);唾液腺,大脑 (大脑CT) 中观察到的最高器官剂量.
- 预测的癌症发病率最高的LAR包括结肠和膀 (全腹CT),结肠,膀和乳房 (泌尿图CT),乳房和肺部 (胸部CT) 和甲状腺 (大脑CT).
- 性腺和甲状腺通常显示LAR最低,除了脑CT扫描.
结论:
- 该研究澄清了儿童单次CT扫描对癌症发病率LAR的器官剂量贡献.
- 这些发现强调了辐射安全措施的关键重要性,以尽量减少儿科患者不必要的辐射暴露.
- 提供了儿童CT成像中风险益处评估的基本数据.
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