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Updated: Jan 11, 2026

In Vitro Differentiation of Human CD4+FOXP3+ Induced Regulatory T Cells (iTregs) from Naïve CD4+ T Cells Using a TGF-β-containing Protocol
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In Vitro Differentiation of Human CD4+FOXP3+ Induced Regulatory T Cells (iTregs) from Naïve CD4+ T Cells Using a TGF-β-containing Protocol

Published on: December 30, 2016

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FOXP3的表达取决于细胞类型特定的 cis-regulatory 元素和转录因子电路.

Jennifer M Umhoefer1, Maya M Arce1, Sivakanthan Kasinathan2

  • 1Gladstone-UCSF Institute of Genomic Immunology, San Francisco, CA 94158, USA; Department of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA; Biomedical Sciences Graduate Program, University of California, San Francisco, San Francisco, CA 94143, USA.

Immunity
|November 14, 2025
PubMed
概括

研究人员确定了控制T细胞中FOXP3基因表达的调控元素. 这揭示了FOXP3在调节性T细胞 (Treg细胞) 和常规T细胞 (Tconv细胞) 中跨物种的特异性调节.

关键词:
克里斯普尔是什么意思?克里斯普尔是什么意思?这是FOXP3P3的.在T细胞,T细胞.增强剂是一种增强剂.表观遗传学是指表观遗传学.基因调节 基因调节 基因调节监管T细胞的监管性T细胞转录因子是一种转录因子.

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