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Updated: Jan 11, 2026

Adenoviral Gene Therapy for Diabetic Keratopathy: Effects on Wound Healing and Stem Cell Marker Expression in Human Organ-cultured Corneas and Limbal Epithelial Cells
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Adenoviral Gene Therapy for Diabetic Keratopathy: Effects on Wound Healing and Stem Cell Marker Expression in Human Organ-cultured Corneas and Limbal Epithelial Cells

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皮表皮生长因子受体通过YAP-CCN2依赖的方式促进糖尿病视网膜纤维化

Wei Zhang1, Xiaopei Zhang2, Kexin Chen2

  • 1Department of Ophthalmology, People's Hospital of Hotan District, Xinjiang Uygur Autonomous Region, China; Tianjin Eye Hospital, Tianjin Key Lab of Ophthalmology and Visual Science, Tianjin Eye Institute, Clinical College of Ophthalmology Tianjin Medical University, Tianjin, 300020, China.

Experimental eye research
|November 14, 2025
PubMed
概括

糖尿病视网膜病变会通过视网膜纤维化导致视力丧失. 向视网膜血管内皮细胞中的表皮生长因子受体 (EGFR) 信号,可以通过抑制穆勒细胞激活和细胞外基质沉积来减少纤维化.

关键词:
结合性组织生长因子糖尿病视网膜病变 - 糖尿病视网膜病变皮肤表皮生长因子受体.视网膜纤维化发生.是的 - 相关蛋白质.

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