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药理上抑制乳酸盐可以减轻术后认知功能障碍

Wei Wang1, Wenqin Song1, Ping Gong2

  • 1Department of Anesthesiology, Renmin Hospital of Wuhan University, Wuhan 430060, China.

Experimental neurology
|November 14, 2025
PubMed
概括

抑制大脑中的乳酸积累可能提供神经保护,防止手术后认知功能障碍 (POCD). 向乳酸通路在POCD模型中改善了认知功能和突触可塑性.

关键词:
乳酸盐是一种乳酸盐.线粒细胞衰变 (mitophagy) 是一种神经衰变的过程.手术后的认知功能障碍热灭菌的发生.在SNAP25中使用SNAP.

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