评估修改后的Centor标准作为一个查工具,在聚合酶链反应测试和抗生素使用前用于VA群体中的A组链球菌喉炎
Logan Schmaltz1, Jessica A Dietz2, Kimberly D P Hammer3
1University of North Dakota, School of Medicine, Grand Forks, North Dakota, USA.
概括
修改后的Centor标准 (MCC) 是诊断A组链球菌 (GAS) 喉炎的不可靠工具. 它的使用并没有改善快速分子检测测试或GAS的抗生素处方准确性.
科学领域:
- 传染性疾病 传染性疾病
- 临床诊断 临床诊断 临床诊断
- 公共卫生 公共卫生
背景情况:
- 甲型 estreptococcal (GAS) 喉炎是一种常见的细菌感染.
- 修改后的Centor标准 (MCC) 或McIsaac标准是GAS的临床查工具.
- 准确的诊断对于指导适当的抗生素治疗和预防并发症至关重要.
研究的目的:
- 评估MCC的临床实用性,用于查疑似GAS喉炎患者.
- 评估MCC对快速分子测定测试 (Xpert Xpress Strep A PCR) 的影响.
- 分析MCC对GAS喉炎抗生素处方模式的影响.
主要方法:
- 对来自法戈VA医疗保健系统的263名成年门诊病例记录的回顾性审查 (2021年3月至2022年11月).
- 患者接受了Xpert Xpress Strep A PCR测试,以怀疑GAS炎.
- 根据记录的患者症状计算MCC得分.
主要成果:
- 大多数患者 (54.8%) 的MCC得分为1或以下.
- 临床医生记录的MCC得分仅记录在6%的遭遇中.
- 在预测阳性PCR测试时,MCC表现出低灵敏度和积极的预测值.
- 14.8%的患者接受了抗生素尽管负面或取消了PCR测试.
- 在39.3%的病例中,在PCR结果出现之前,已经开了抗生素.
结论:
- 该MCC是一个不可靠的预测阳性Strep A PCR测试结果.
- 需要加强对临床医生的教育,以适当地利用A型链杆菌PCR测试.
- 建议在怀疑GAS喉炎时改善抗生素管理.
相关概念视频
Acute Pharyngitis
3.8K
Introduction
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
3.8K
Antimicrobial Effectiveness
889
The effectiveness of antimicrobial agents depends on various factors influencing their ability to eliminate microbial populations. Larger microbial populations require more time for complete eradication, emphasizing the importance of population size analysis when evaluating antimicrobial efficacy.Microbial resistance to antimicrobial agents varies significantly. Highly resilient microorganisms include endospores, gram-negative bacteria, and non-enveloped viruses, while prions are exceptionally...
889


