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Updated: Jul 21, 2026

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一个人类相关的体外气膜上皮质屏障模型,以评估吸入污染物的危险性

Joshua W P Bateman1, Kirsty Meldrum1, Sarah M Mitchell1

  • 1In Vitro Toxicology Group, Institute of Life Science 1, Swansea University Medical School, Swansea, SA2 8PP, UK.

Scientific reports
|November 14, 2025
PubMed
概括

开发了一种使用人类膜上皮细胞 (hAELVi),NCI-H441细胞和差异化THP-1细胞的新三细胞共培模式. 这种体外模型准确地模仿了人体膜屏障,用于吸入物质的毒理测试.

关键词:
气管是指气管中的一个.在体外 (in vitro) 的情况下.多细胞模型多细胞模型毒理学 毒理学 毒理学

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Alveoli and Alveolar Ducts01:26

Alveoli and Alveolar Ducts

The respiratory zone of the human body, which stands in contrast to the conducting zone, comprises the structures that actively participate in the exchange of gases. The initiation of this zone is marked by the terminal bronchioles converging into respiratory bronchioles, the tiniest bronchiole classification. The respiratory bronchioles give way to the alveolar ducts that opens into a congregation of alveoli. Actively involved in gas exchange, alveoli resemble tiny sacs similar to clusters of...