用非复制性抗生素耐药性免费DNA疫苗对SARS-CoV-2的双对应尖端免疫能诱导对多种病毒变异的免疫力

Jaime Larraga1,2, Pablo Nogales-Altozano1,3, Laro Gomez-Marcos1

  • 1Centro de Investigación en Sanidad Animal, Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria, Consejo Superior de Investigaciones Científicas (CISA-INIA-CSIC), Valdeolmos, Madrid, Spain.

Scientific reports
|November 14, 2025
PubMed
概括

一种新的DNA疫苗 (pPAL) 表达了多种严重急性呼吸系统综合征冠状病毒-2 (SARS-CoV-2) 抗原,保护小鼠免受致命变异的影响. 这种可适应的平台显示了未来COVID-19疫苗接种战略的前景.

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