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Updated: Jan 11, 2026

gDNA Enrichment by a Transposase-based Technology for NGS Analysis of the Whole Sequence of BRCA1, BRCA2, and 9 Genes Involved in DNA Damage Repair
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在未经选择的ER-Low/HER2-阴性乳腺癌中生殖系BRCA1/2突变的患病率

Ji Won Yoo1, Jinyoung Byeon2, Woong Ki Park1

  • 1Division of Breast Surgery, Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.

Annals of surgical oncology
|November 14, 2025
PubMed
概括

低雌激素受体 (ER) 乳腺癌的BRCA1/2突变率与三阴性乳腺癌 (TNBC) 类似. 目前的指导方针可能错过了携带者;建议将基因检测扩展到包括低ER瘤.

关键词:
这是BRCA1/2突变.低ER的乳腺癌 - 乳腺癌基因检测指南 基因检测指南遗传性乳腺癌是一种遗传性乳腺癌.三重阴性乳腺癌是什么

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