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与非贫血铁缺乏症性结肠炎相关的因素
Shogo Kitahata1, Mai Fukumoto2, Kana Matsuoka2
1Gastroenterology Center, Ehime Prefectural Central Hospital, Kasugamachi, Matsuyama, Ehime, 790-0024, Japan. shogo_kitahata@yahoo.co.jp.
非贫血性铁缺乏症影响三分之一的性结肠炎患者. 女性性别和缺少粘膜愈合是关键的危险因素,即使没有贫血.
科学领域:
- 胃肠病学 胃肠病学
- 血液学 血液学 血液学
- 内部医学 内部医学
背景情况:
- 非贫血性铁缺乏症在性结肠炎 (UC) 患者中很普遍.
- 它经常被忽视,影响患者的生活质量.
- 了解相关因素对于及时干预至关重要.
研究的目的:
- 在日本UC患者中确定与非贫血铁缺乏症相关的因素.
- 改善对该人口的铁状况的管理.
主要方法:
- 日本112名非贫血性UC患者的横截面研究 (2021年4月至2023年3月).
- 铁缺乏症是由费里水平定义的 (<100 ng/mL有疾病活性,<30 ng/mL没有).
主要成果:
- 非贫血铁缺乏症的患病率为33.9%.
- 独立预测因素包括女性性别 (aOR:15.40) 和非粘膜愈合 (aOR:18.10).
- 临床缓解,普得尼索隆使用,CRP和转林和没有显著的关联.
结论:
- 女性性别和非粘膜愈合是UC非贫血缺铁的重要独立因素.
- 建议对具有这些特征的UC患者进行铁状况监测,不论贫血.
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