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在中年消防员中,急性活体消防对心室动脉合和脉动后负荷的影响
João L Marôco1,2, Abbi D Lane3, Sushant M Ranadive4
1Integrative Human Physiology Laboratory, Manning College of Nursing & Health Sciences, University of Massachusetts Boston, Boston, Massachusetts, USA.
Physiological reports
|November 15, 2025
概括
消防工作急剧增加后负荷和动脉弹性,损害中年男性消防员的腹腔动脉合和冠状动脉 perfusion. 这些心血管变化凸显了与老年消防员和值班心脏事件相关的潜在风险.
科学领域:
- 心血管生理学心血管生理学
- 职业健康 职业健康 职业健康
背景情况:
- 消防施加显著的生理压力,增加后负载,并可能导致腹腔动脉合不匹配.
- 这种不匹配可能会导致冠状动脉低,并增加值班心脏事件的风险,特别是在老年消防员中.
研究的目的:
- 调查急性灭火对腹腔血管合和中年男性消防员后负荷动态的影响.
- 在消防模拟期间评估浪费压力力 (Ew),大动脉储功能和冠状动脉 perfusion 的变化.
主要方法:
- 22名男性消防员 (40-59岁) 接受了高强度的消防演习.
- 使用心声学和度学衍生的脉冲波分析来测量心脏体积,浪费压力 (Ew),大动脉储功能和心室-动脉合 (Ea/Ees比率).
- 巴克伯格指数被用来估计在演习之前和之后的冠状动脉 perfusion.
主要成果:
- 消防工作显著降低了中风量,浪费压力 (Ew),大动脉储功能和巴克伯格指数,表明冠状动脉输液减少.
- 动脉弹性 (Ea) 与心室末性弹性 (Ees) 的比率因Ea的升高而增加,这表明心室-动脉合受损.
- 心率变化与浪费压力和大动脉储功能相关.
结论:
- 中年消防员在消防后经历了急性心血管应变,其特点是冠状动脉输液减少和心室动脉合改变.
- 该研究强调了消防对心血管血液动力学的影响,但指出,心率混限制了对心室动脉相互作用和脉动后负载的最终结论.
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