在全膝关节整形术患者全身麻醉后出现动荡的预测模型的开发和验证
Li Wang1, Xin-Xiang Luo2, Man-Ni Yang2
1Ya'an Hospital of Traditional Chinese Medicine, Ya'an, China.
Medicine
|November 15, 2025
概括
年龄较大,麻醉时间较长,低温,ASA分类较高和第一次全身麻醉增加了全膝关节整形术 (TKA) 患者手术后动荡的风险. 预测性名录图有助于识别有针对性的干预措施的风险人群.
科学领域:
- 麻醉学 麻醉学
- 整形外科手术 整形外科手术
- 患者安全 患者安全
背景情况:
- 在接受全膝关节整形手术 (TKA) 的患者中,术后动作是令人担忧的.
- 识别风险因素和开发预测模型可以改善患者的治疗结果.
- 一般麻醉通常用于TKA手术.
研究的目的:
- 确定TKA患者术后动荡的独立风险因素.
- 构建和验证术后动荡的预测名图.
- 加强手术前风险评估,指导针对性的干预措施.
主要方法:
- 在全身麻醉下对957名TKA患者的回顾性分析.
- 单变量和多变量逻辑回归用于风险因素识别.
- 开发和验证使用AUC,校准和决策曲线的预测名录.
主要成果:
- 在10.45%的患者中出现了术后动荡.
- 确定了独立的风险因素:年龄> 75岁,麻醉时间> 3小时,手术期间低温,ASA分类> II,首次全身麻醉.
- 诺米图表显示出良好的区分能力 (AUC 0.830培训,0.817验证) 和临床适用性.
结论:
- 一个经过验证的诺姆图有效地预测了TKA患者手术后动荡风险.
- 该模型有助于临床医生在手术前识别高风险患者.
- 可以实施有针对性的干预措施,以改善患者安全和康复结果.
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