由BosR控制的DNA结合控制了Borrelia burgdorferi中的RpoS依赖和独立基因表达

André A Grassmann1,2, Melissa A McLain1, Michael R Freeman1,3

  • 1Department of Medicine, University of Connecticut Health, Farmington, Connecticut, USA.

Molecular microbiology
|November 15, 2025
PubMed
概括

BosR通过RpoS依赖和独立的途径调节Borrelia burgdorferi的基因表达,影响毒性和基因组维护. 结合DNA对于其全球调节功能在适应哺乳动物宿主方面至关重要.

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