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Updated: Jan 11, 2026

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一个计算机辅助的药物重新定位:针对GroEL的抗菌剂

Dongdong Zhang1,2, Feng-Biao Guo1,2, Haotian Li2

  • 1Department of Respiratory and Critical Care Medicine, Zhongnan Hospital of Wuhan University, School of Pharmaceutical Sciences, Wuhan University, Wuhan, China.

British journal of pharmacology
|November 15, 2025
PubMed
概括

药物重新定位为新抗生素提供了具有成本效益的途径. 一个新的计算工作流确定了现有的药物,达普罗杜沙特和埃泽蒂米布,对细菌有效,与排泄抑制剂结合时具有协同作用的潜力.

关键词:
格罗埃尔 (GroEL) 是一个古老的城市.抗生素抗生素是一种抗生素.在生产状态下.药物组合是药物组合.药物重用是为了改变药物的用途.

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