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2-amido-3-aryl-4-methyl-thiazole衍生物作为广泛的抗鼻病毒药物

Sileshi Abera Ayele1, Hye Lim Lee2, Céline Sablon3

  • 1Infectious Diseases Therapeutic Research Center, Korea Research Institute of Chemical Technology, Daejeon, 34114, Republic of Korea; Department of Medicinal Chemistry and Pharmacology, University of Science and Technology, Republic of Korea.

European journal of medicinal chemistry
|November 15, 2025
PubMed
概括

新的提亚衍生物通过抑制酸4-酶IIIβ (PI4KIIIβ) 来表现出对人类犀病毒 (RV) 的强有力的抗病毒活性. 化合物2e (KR-27452) 是开发广泛的抗RV疗法的有希望的候选物.

关键词:
广谱抗病毒药物 广谱抗病毒药物人类犀利病毒.这是一种PI4KIIIβ抑制剂.在RV-C15中使用RV-C15铁醇衍生品 铁醇衍生品

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