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Updated: Jan 11, 2026

Facile Preparation of 4-Substituted Quinazoline Derivatives
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Published on: February 15, 2016

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研究新型quinazolin-4(3H) -one衍生物的合成和结构-活性关系,作为具有免疫调节活性的Toll-like受体7和8激活剂

Nika Strašek Benedik1, David Lukić1, Tjaša Slokan1

  • 1University of Ljubljana, Faculty of Pharmacy, Department of Pharmaceutical Chemistry, Aškerčeva 7, 1000, Ljubljana, Slovenia.

European journal of medicinal chemistry
|November 15, 2025
PubMed
概括

研究人员开发了新型quinazolinone衍生物,可以激活托尔类受体 (TLRs) 7和8. 这些化合物显示出作为免疫调节剂的潜力,其中一种衍生物在体内有效抑制瘤生长.

关键词:
激进主义者的激进主义者基纳佐利诺 (quinazolinone) 是一种可以小分子分子的小分子.综合合成 综合合成在TLR7中,在TLR8中,收费类受体的收费类受体

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