部硬及其与放射治疗后食障碍的相关性在头部和部癌症中
Junki Ono1, Hideaki Nishi1, Sumie Takashima1
1Department of Otolaryngology Head and Neck Surgery Graduate School of Biomedical Sciences, Nagasaki University, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan.
Auris, nasus, larynx
|November 15, 2025
概括
头癌的放射治疗增加了部硬,可能会损害喉升高 (LE) 并导致食障碍. 减少喉升高距离 (LED) 与治疗后吞困难有显著联系.
科学领域:
- 在瘤学瘤学.
- 辐射疗法 辐射疗法
- 吞障碍 吞障碍 吞障碍
背景情况:
- 缺食症是用于头癌的放射治疗的常见副作用.
- 部硬可能会导致放射治疗后的吞功能障碍.
研究的目的:
- 评估头癌放射治疗后宫硬和吞功能障碍之间的关联.
- 为了研究部硬在放射治疗后食障碍症中的作用.
主要方法:
- 放射治疗前和治疗后6个月进行了超声波 (剪切波弹性图像) 和吞功能测试.
- 测量了硬肌硬度,透吸收量表 (PAS) 评分,状骨位移和喉升高延迟时间.
主要成果:
- 放射治疗后部硬度显著增加,特别是在激光照射组.
- 喉升高距离 (LED) 的减少与放射治疗后的消化不良显著相关 (OR:0.67,p=0.035).
结论:
- 剪波弹性图证实了放射治疗后部硬度增加.
- 喉升高功能受损,以减少的LED表示,可能会在头癌放射治疗后导致食障碍的发展.
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