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brojlers中的mycobiome时间和功能动态:生态视角对细菌-真菌相关性和料添加剂的影响
Ana Fonseca1, Sophia Kenney1, John Boney2
1Department of Animal Science, The Pennsylvania State University, University Park, PA, United States; One Health Microbiome Center, The Pennsylvania State University, University Park, PA, United States.
Poultry science
|November 15, 2025
概括
肉肠道真菌群体随着年龄而变化,而不是饮食. 菌种群随着时间的推移而变化,影响肠道生态和与禽类健康至关重要的细菌相互作用.
科学领域:
- 动物科学动物科学
- 微生物学 微生物学
- 肠道生态学肠道生态学
背景情况:
- 肉肠道菌组虽然比细菌少,但对肠道生态至关重要,但仍未得到充分研究.
- 了解真菌社区动态对于优化家禽健康和生产至关重要.
研究的目的:
- 调查影响肉排泄物相关的真菌群体的时间,饮食和生态因素.
- 分析真菌群落和细菌微生物群之间的相关性.
- 评估料添加剂 (抗生素,精油,益生菌) 对真菌动态的影响.
主要方法:
- 在21天内从320只肉的便样本中进行了枪支元基因组测序.
- 分析真菌的多样性,组成,跨王国相关性和功能概况.
- 在四种饮食治疗中进行比较:基底,抗生素,精油和益生菌.
主要成果:
- 在真菌群体中,阿斯科米科塔和巴西迪奥米科塔占据主导地位.
- 菌类丰富性和均性随宿主年龄显著增加,表明年龄驱动的继承,独立于饮食.
- 观察到明显的与年龄相关的真菌集群,早期的Candida albicans主导地位转移到Fusarium和Malassezia.
- 跨王国分析揭示了真菌和细菌群落之间的时间相关性,特定的真菌与致病性和有益细菌都有关联.
- 料添加剂对整个真菌多样性指标的影响最小.
结论:
- 主体年龄是肉排泄物真菌继承的主要驱动因素.
- 在真菌和细菌群体的同时发生的变化表现出时间可塑性.
- 多王国生态方法对于理解和改善家禽肠道健康至关重要.
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