相关实验视频

Updated: Jan 11, 2026

Preparation of Primary Neurons for Visualizing Neurites in a Frozen-hydrated State Using Cryo-Electron Tomography
09:59

Preparation of Primary Neurons for Visualizing Neurites in a Frozen-hydrated State Using Cryo-Electron Tomography

Published on: February 12, 2014

79.8K

通过cryoCLEM引导的cryoET可视化的3D宏分子架构.

Charlie Lovatt1, Thomas O'Sullivan1, Clara Ortega-de San Luis2

  • 1Astbury Centre for Structural Biology, School of Biomedical Sciences, Faculty of Biological Sciences, University of Leeds, Leeds, UK.

Structure (London, England : 1993)
|November 15, 2025
PubMed
概括

科学家们可视化了小鼠海马体内记忆引擎突触的3D结构. 这揭示了这些存储记忆的神经元连接中的多样化的分子组织,为记忆形成提供了洞察力.

关键词:
英格拉姆 (Engram) 是一个电子书.记忆 记忆 记忆 记忆 记忆冷-CLEMEM 的使用方法.化-ETET可以使用.冷电子断层扫描 (Cryo-electron tomography) 是一种电子断层扫描技术.组织内结构结构 组织内结构突触突触是指突触中的突触.

更多相关视频

Do's and Don'ts of Cryo-electron Microscopy: A Primer on Sample Preparation and High Quality Data Collection for Macromolecular 3D Reconstruction09:25

Do's and Don'ts of Cryo-electron Microscopy: A Primer on Sample Preparation and High Quality Data Collection for Macromolecular 3D Reconstruction

Published on: January 9, 2015

46.9K
Flash-and-Freeze: A Novel Technique to Capture Membrane Dynamics with Electron Microscopy10:01

Flash-and-Freeze: A Novel Technique to Capture Membrane Dynamics with Electron Microscopy

Published on: May 1, 2017

14.6K

相关概念视频

Cryo-electron Microscopy01:28

Cryo-electron Microscopy

Conventional electron microscopy (EM) involves dehydration, fixation, and staining of biological samples, which distorts the native state of biological molecules and results in several artifacts. Also, the high-energy electron beam damages the sample and makes it difficult to obtain high-resolution images. These issues can be addressed using cryo-EM, which uses frozen samples and gentler electron beams. The technique was developed by Jacques Dubochet, Joachim Frank, and Richard Henderson, for...
4.1K