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Updated: Jan 11, 2026

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F-53B通过触发线粒体功能障碍来触发卵巢颗粒细胞衰老和卵巢功能障碍

Zhiyuan Wang1, Yang Su2, MengQin Wang2

  • 1Department of Medical Genetic and Fetal Medicine, Fujian Provincial Maternity and Children's Hospital, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, China; Quanzhou Women's and Children's Hospital, Reproductive Medicine Center, China.

Chemico-biological interactions
|November 15, 2025
PubMed
概括

6:2 化聚甲基乙烯硫酸盐 (F-53B),一种PFAS,通过cGAS-STING-IRF3通路触发卵巢颗粒细胞衰老. 这导致女性生殖功能障碍,影响生育能力,并可能导致过早的卵巢衰竭.

关键词:
F53BB F53BB F53B F53B F53B F53B F53B F53炎症 炎症是一种炎症.卵巢 卵巢 卵巢氧化应激是一种氧化应激.衰老是一种衰老.

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