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Updated: Jan 11, 2026

Yeast Luminometric and Xenopus Oocyte Electrophysiological Examinations of the Molecular Mechanosensitivity of TRPV4
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Yeast Luminometric and Xenopus Oocyte Electrophysiological Examinations of the Molecular Mechanosensitivity of TRPV4

Published on: December 31, 2013

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PPARγ 连接体激活了TRPA1 离子通道

Franziska Guenther1, Mohua Kibria Mumu2, Clive Gentry2

  • 1Wolfson SPaRC, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, SE1 1UL, United Kingdom; Institute for Physiology and Pathophysiology, University of Erlangen-Nuremberg, Universitaetsstrasse 17, 91054, Erlangen, Germany.

European journal of pharmacology
|November 15, 2025
PubMed
概括

氧酶增殖器激活受体玛 (PPARγ) 连接体,包括格利塔,激活感官神经元中的TRPA1通道. 这种激活导致小鼠的疼痛反应,这表明PPARγ配体在TRPA1-介导的感觉中发挥了作用.

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