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Updated: May 5, 2026

Comprehensive Assessment of Germline Chemical Toxicity Using the Nematode Caenorhabditis elegans
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混合物效应的慢性:转基因C. elegans多重毒性终点的敏感性差异和联合毒性相互作用的评估

Peng Huang1, Shu-Shen Liu2, Jiake Li1

  • 1State Key Laboratory of Water Engineering Ecology and Environment in Arid Area, Xi'an University of Technology, Xi'an, Shaanxi 710048, China; Department of Municipal and Environmental Engineering, School of Water Resources and Hydro-Electric Engineering, Xi'an University of Technology, Xi'an, Shaanxi 710048, China.

Toxicology letters
|November 16, 2025
PubMed
概括

杀虫剂混合物 (阿尔迪卡布,甲米多,三) 在C. elegans中显示出度依赖的毒性. 相互作用从对抗转向协同作用,挑战混合物毒性评估.

关键词:
慢性毒性 慢性毒性这就是EquRayRay.混合物的毒性 混合物的毒性协同-敌对的热图.在 UD 射线上.

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Toxicity tests in animals are grounded on two main assumptions: first, the effects observed in laboratory animals can be extrapolated to humans, especially when adjusted for body surface area; second, high-dose exposure in animals is essential to identify potential human hazards from lower doses. This is based on the quantal dose-response concept, which faces the challenge of extrapolating results from relatively few test animals to much larger human populations. For example, a 0.01% incidence...
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