来自伊朗西部的狗患有内脏莱什曼病
Alireza Sazmand1, Georgiana Deak2, Ali Kalantari-Hesari3
1Department of Pathobiology, Faculty of Veterinary Medicine, Bu-Ali Sina University, 6517658978 Hamedan, Iran.
Veterinary parasitology, regional studies and reports
|November 16, 2025
概括
在以前非特有的伊朗地区,在狗身上检测到Leishmania infantum. 这一发现凸显了对犬类监测的必要性,以控制动物和人类的这种寄生虫感染.
科学领域:
- 兽医寄生虫学 兽医寄生虫学
- 传染性疾病 传染性疾病
- 分子流行病学分子流行病学
背景情况:
- 莱什曼尼亚婴儿是一种由沙传播的显著动物性寄生虫,狗作为主要储存器.
- 由于其在疾病传播中的作用和动物传播传播的潜力,犬类莱什曼病引起了公众健康的关注.
- 伊朗西部省份以前不被认为是莱什曼尼亚婴儿的特有地区.
研究的目的:
- 在伊朗哈梅丹 (Hamedan) 的狗中首次检测到Leishmania infantum,此前该地区被认为是非特有地区.
- 描述与这些狗的Leishmania婴儿感染相关的临床和寄生虫学发现.
- 强调持续监测犬种群对疾病控制的重要性.
主要方法:
- 对六只患有皮肤病变和身体状况不佳的杂交狗进行临床检查.
- 对Leishmania amastigotes的印记涂抹和组织痕的显微镜检查.
- 脏,皮肤和淋巴结样本的组织病理学分析.
- 从皮肤病变中提取的基因组DNA的常规PCR和DNA测序,以确认Leishmania spp.
主要成果:
- 在所有被检查的狗中,Leishmania infantum amastigotes在显微镜上被识别出来.
- 临床症状包括缓解症,淋巴腺病变和各种粘膜皮肤病变与斑疹性皮肤炎.
- PCR和测序证实了感染狗中的Leishmania婴儿DNA的存在.
结论:
- 这项研究证实了伊朗西部犬群中Leishmania infantum的存在,扩大了已知的流行地区.
- 这些发现强调了实施犬类莱什曼病定期监测计划的必要性.
- 狗群中有效的控制策略对于降低人类和动物传染莱什曼尼病的风险至关重要.
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