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Updated: Jan 11, 2026

Reverse Yeast Two-hybrid System to Identify Mammalian Nuclear Receptor Residues that Interact with Ligands and/or Antagonists
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对核受体转录因子的潜在内源性脂质配体 类固醇因子-1 核受体转录因子

Alexis N Campbell1, Raymond D Blind2

  • 1Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN, 37232, USA.

Advances in biological regulation
|November 16, 2025
PubMed
概括

类固醇原因子1 (SF-1) 调节对发育和组织功能至关重要的基因. 本综述检查了控制SF-1活性的潜在脂质配体,这对于理解诸如上腺皮质癌等疾病至关重要.

关键词:
核激素受体连接体 核激素受体连接体酸氨基醇和螺旋脂类受体受体通过受体介导的转录激活.X射线晶体学和晶体结构

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