摄入添加库尔库的乳清蛋白缩剂在消耗性运动后积极调节肠道健康参数
Stephanie Michelin Santana Pereira1, Kelly Aparecida Dias1, Lívya Alves Oliveira1
1Laboratory of Vitamin Analysis, Department of Nutrition and Health, https://ror.org/0409dgb37Universidade Federal de Viçosa, Av. Peter Henry Rolfs, s/n - Campus Universitário, Viçosa, MG, 36570-900, Brasil.
乳清蛋白缩剂 (WPC) 和黄素 (CCM) 补充剂有助于在彻底炼后维持大鼠的肠道健康. 这些补充剂保留了短链脂肪酸 (SCFA) 生产和抗氧化活性,减轻了运动引起的肠道压力.
科学领域:
- 运动生理学 运动生理学
- 胃肠病学 胃肠病学
- 营养科学 营养科学
背景情况:
- 消耗性运动 (EE) 对肠道健康产生负面影响,增加了肠道的透性和炎症.
- 饮食干预措施,如乳清蛋白缩物 (WPC) 和黄素 (CCM),由于它们的抗炎和抗氧化特性,显示出减轻这些影响的潜力.
研究的目的:
- 为了研究WPC+CCM和CCM补充剂对Wistar大鼠肠道健康的影响,这些大鼠接受了彻底的运动.
- 评估对短链脂肪酸 (SCFA) 生产,氧化应激标志物和肠道完整性的影响.
主要方法:
- 威斯塔尔老鼠被分为六组,在完整的游泳测试之前,在四周内补充WPC + CCM或CCM.
- 运动后,分析包括SCFA含量,氧化应激标记物 (甲,碳化蛋白),抗氧化酶活性,基因表达 (Nrf2,NF-κB,奥克卢丁,克劳丁) 和结肠组织形态测试.
主要成果:
- SCFA含量和malondialdehyde水平保持稳定;然而,WPC + CCM增加了碳化蛋白度.
- 氧化减少,而大多数抗氧化酶增加在补充组. 随着WPC+CCM,nrf2,NF-κB和奥克卢丁的表达保持不变,克劳丁的表达增加.
- CCM补充剂增强了粘膜厚度和保存了杯状细胞.
结论:
- 补充WPC + CCM有效地预防了因消耗性运动引起的氧化应激增加和炎症.
- 补充维护SCFA的生产,抗氧化活性,以及在运动后大鼠的肠道完整性.
- 单独使用CCM也在保护肠道粘膜结构方面表现出好处.
更多相关视频
12:32High-resolution Respirometry to Measure Mitochondrial Function of Intact Beta Cells in the Presence of Natural Compounds
Published on: January 23, 2018
08:34Investigating the Alleviating Effects of Bacillus cereus Administration on Colitis through Gut Microbiota Modulation
Published on: July 27, 2022
相关概念视频
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
Exercise and Muscle Performance
Endurance exercises
Endurance exercises involve running, swimming, or cycling, which require repetitive movements with low force output. When a person engages in endurance exercise, a few noticeable changes occur in their skeletal muscles. For instance, the number of capillaries...
Protein Absorption
Overview of Protein Metabolism
Amino acids play various roles in the body once they are absorbed into cells. They are restructured...
Protein Digestion
