胎儿大小,妊娠年龄和5岁的认知表现:四个国家队列的研究
Xuan Zhao1,2, Robert Eves1,3, Siobhan Quenby2
1Department of Psychology, Lifespan Health and Wellbeing Group, University of Warwick, Warwick, UK.
概括
胎儿的大小不会改变妊娠年龄和儿童智商之间的关联. 然而,对于妊娠年龄来说出生小 (SGA) 与较低的智商有关,特别是在37周出生的婴儿中.
科学领域:
- 围产期流行病学 围产期流行病学
- 发展心理学 发展心理学
- 儿科健康 儿科健康
背景情况:
- 胎儿的大小和妊娠年龄对于妊娠期的分娩时间至关重要.
- 以前的研究表明胎儿大小,妊娠年龄和认知结果之间存在关联.
- 了解这些关系对于优化儿童发育至关重要.
研究的目的:
- 调查胎儿大小是否能缓和妊娠年龄 (37-41周) 与儿童智力之间的关联.
- 分析胎儿大小类别 (对于妊娠年龄大 - LGA,适合妊娠年龄 - AGA,适合妊娠年龄小 - SGA) 对认知结果的影响.
- 评估智商指数 (IQ) 在5岁时的得分,与出生参数相关.
主要方法:
- 来自四个国际队列 (美国,英国,爱尔兰,澳大利亚) 的统一数据.
- 使用芬顿图表 (SGA,AGA,LGA) 分类的胎儿大小.
- 线性模型和对比分析用于评估5岁的智商分数.
主要成果:
- 关于儿童智商,胎儿大小和妊娠年龄之间没有发现显著的相互作用.
- 出生时对于妊娠年龄来说小 (SGA) 始终与较低的智商有关,而不是与妊娠年龄相适应 (AGA) 相比.
- 怀孕年龄大 (LGA) 与智商差异没有显著关联.
结论:
- 胎儿大小并不能调节妊娠年龄和IQ之间的联系.
- 无论妊娠年龄如何,对于妊娠年龄的小 (SGA) 状态都与较差的认知结果有关.
- 与41周相比,在SGA 37周出生的儿童中观察到临床上有意义的智商下降.
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