结肠镜检查后结肠直肠癌的患病率下降:系统性审查和元分析
Lechang Zhang1, Tong Su, Tong Xiao
1Department of Gastroenterology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan Shandong 250021, People's Republic of China.
Surgical laparoscopy, endoscopy & percutaneous techniques
|November 17, 2025
概括
结肠镜后结肠直肠癌 (PCCRC) 影响了2005-2021年期间查的4.0%的患者. 提高结肠镜检查的质量是减少PCCRC的关键,并加强癌症预防工作.
科学领域:
- 胃肠病学 胃肠病学
- 在瘤学瘤学.
- 公共卫生 公共卫生
背景情况:
- 结肠直肠癌 (CRC) 的负担在全球范围内不断增加,而查结肠镜检查对于预防至关重要.
- 结肠镜后结肠直肠癌 (PCCRC) 是这种查方法的一个局限性.
- 在3年内诊断的PCCRCs (PCCRC-3y) 是一个重大问题.
研究的目的:
- 为了确定PCCRC-3y.的综合流行率.
- 突出提高内镜质量指标的重要性.
- 为了有效地减轻PCCRC-3y的负担.
主要方法:
- 通过2024年6月进行的系统文献搜索.
- 包括单中心,多中心和基于人口的研究报告PCCRC-3y流行率.
- 使用世界内镜组织的方法和质量指标的定量评估进行了聚合的患病率估计.
主要成果:
- 分析了包括25504个PCCRC在内的17项研究.
- 聚合的PCCRC-3y患病率为5.5% (95% CI:4.9-6.2%). 综合的PCCRC-3y患病率是5.5% (95% CI:4.9-6.2%). 综合的PCCRC-3y患病率是5.5% (95% CI:4.9-6.2%). 综合的PCCRC-3y患病率是5.5% (95% CI:4.9-6.2%).
- PCCRC-3y的患病率显著下降,从6.7% (1992-2015) 下降到4.0% (2005-2021),P=0.01. 这一数字是指PCCRC-3y的患病率从6.7% (1992-2015) 下降到4.0% (2005-2021),P=0.01.
- 在近肠 (8.7%) 与远肠 (4.6%) 相比,观察到更高的患病率.
结论:
- 在2005-2021年期间,PCCRC-3y的综合流行率为4.0% (95% CI:2.9-5.6%),表明显著下降.
- 这种患病率作为CRC检测,预防和结肠镜检查质量改善的基准.
- 确定的内镜质量指标为提高结肠镜标准提供了指导.
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