案例报告:由于接触阿育吠陀草药,导致严重的中毒
Gabriella Cericola1, Alexander Puzik1, Sarah Salou1
1Division of Pediatric Hematology and Oncology, Faculty of Medicine, Children's Hospital, University Medical Center of Freiburg, University of Freiburg, Freiburg, Germany.
Frontiers in pediatrics
|November 17, 2025
概括
一个孩子 一个孩子
科学领域:
- 环境健康 环境健康
- 毒理学 毒理学 毒理学
- 儿科 儿科 儿科
背景情况:
- 是一种有毒的环境重金属.
- 儿童很容易受到中毒的影响.
- 暴露于可能会损害重要器官和神经系统.
研究的目的:
- 报告儿童严重中毒的情况.
- 为了确定暴露的来源.
- 讨论对阿育吠陀产品安全性的影响.
主要方法:
- 一个4岁男孩的案例研究.
- 临床表现包括贫血,高血压和神经功能障碍.
- 实验室检测结果:基型斑点,血水平升高 (BLL).
主要成果:
- 这个孩子的BLL为123μg/dl.
- 暴露与治疗喘的阿育吠陀草药补充剂有关.
- 化疗导致症状消失,并降低了BLLs.
结论:
- 由于重金属污染,阿育吠陀产品可能会造成健康风险.
- 改善阿育吠陀药品的质量控制至关重要.
- 需要对潜在污染的公众教育,以防止中毒.
相关概念视频
Prevention of Further Absorption of Poison
In cases of acute poisoning, the primary objective is to prevent further absorption of the toxic substance into the body. Immediate interventions using various decontamination techniques targeting the gastrointestinal (GI) tract can achieve this. Decontamination is crucial to prevent poison from entering the systemic circulation, which involves washing affected areas with water and mild soap and removing contaminated clothing. Once external decontamination is done, attention must be turned to...
CNS Depressants: Alcohol and Nicotine
Ethanol, a clear colorless alcohol, has been consumed by humans for millennia, but its effects on the body are far from benign. At lower doses, it induces decreased inhibitions and loquaciousness, leading to its social appeal. However, it can cause severe consequences at higher doses, such as coma and respiratory depression, due to its zero-order elimination kinetics. Chronic ethanol abuse wreaks havoc on multiple organ systems, particularly the CNS and the liver. Abrupt cessation of ethanol...
Drug Toxicity: Overview
Drug toxicity quantifies the harm a compound causes to an organism, varying by dose and potentially impacting whole systems or specific organs like the liver. Toxic reactions may arise from venomous insect or spider bites, with effects ranging from mild symptoms to severe outcomes such as brain damage or death. Common forms of acute poisoning include ethanol intoxication and overdose of pain or fever medications, with substances like GHB and heroin being particularly lethal at doses close to...
Drug Toxicity: Risk factors
Adverse Drug Reactions (ADRs) are potential complications that arise during pharmacotherapy, influenced by multiple risk factors. Age plays a significant role; both neonates and the elderly are at heightened risk due to their respective immature and diminished metabolic and elimination processes. Gender also impacts ADRs, with females experiencing a 1.5 to 1.7-fold greater risk than males, which may be linked to pharmacokinetic, pharmacodynamic, and hormonal differences. Notably, neonates, the...
Pharmaceutical Poisoning: Potential Scenarios
Pharmaceutical poisoning can occur through various channels, impacting an estimated 2 million hospitalized patients in the U.S. annually with serious adverse drug responses. These scenarios encompass both therapeutic uses, such as drug toxicity, where even standard dosages can lead to severe central nervous system depression, and non-therapeutic exposures, including accidental ingestion by children, and environmental and occupational exposures.Unintentional poisonings often involve exploratory...
Pharmaceutical Poisoning: Treatment Strategies
Treatment strategies for poisoning are a critical aspect of emergency medicine, focusing on preventing the absorption of toxins and enhancing their elimination. When a poisoning incident occurs, the first response is to halt exposure and decontaminate the patient, particularly through gastrointestinal (GI) methods if the poison was ingested.Gastrointestinal Decontamination Techniques:Activated charcoal is the cornerstone of GI decontamination. It works through adsorption, binding the toxin to...


