超广场光素血管学基于向视网膜光凝与泛视网膜光凝在多发性糖尿病视网膜病变:一个随机对照试验
Imran Ahmad1, Yousaf Jamal Mahsood2
1Imran Ahmad, (MBBS, MRCS.Ed, FICO, FACS, FCPS, FCPS-Vitreoretina, MHPE) Associate Professor, Department of Ophthalmology, Khyber Medical College, Khyber Teaching Hospital, Peshawar, Pakistan.
Pakistan journal of medical sciences
|November 17, 2025
概括
针对性视网膜光凝 (TRP) 和泛视网膜光凝 (PRP) 对多发性糖尿病视网膜病变同样有效. 然而,PRP对视野指数和平均偏差有负面影响.
科学领域:
- 眼科医生 眼科 眼科
- 视网膜疾病 视网膜疾病
- 糖尿病视网膜病变 - 糖尿病视网膜病变
背景情况:
- 增殖性糖尿病视网膜病变 (PDR) 是糖尿病的一种严重并发症.
- 目前的治疗方法包括泛视网膜光凝 (PRP).
- 超广场成像允许有针对性的治疗方法.
研究的目的:
- 为了比较针对性视网膜光凝血 (TRP) 的安全性和有效性,使用超宽场光素血管学与传统的PRP用于PDR.
- 评估这两种治疗对视觉敏度,黄斑厚度和视野参数的影响.
主要方法:
- 一项随机对照试验,涉及120名患有PDR的患者.
- 患者被随机分配到TRP (准缺血区) 或PRP (常规协议).
- 评估结果包括最佳校正视敏度 (BCVA),中央黄斑厚度 (CMT),平均偏差 (MD) 和视野指数 (VFI).
主要成果:
- 在治疗后,TRP和PRP组之间没有BCVA,CMT,MD或VFI的显著差异.
- 与基线相比,TRP和PRP组的CMT显著改善.
- 与基线相比,PRP组的MD和VFI明显恶化.
结论:
- TRP和PRP在治疗PDR时表现出可比的疗效.
- 与TRP不同,PRP与视野指数的负面影响有关.
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