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Updated: Jan 11, 2026

Preparation of Acute Hippocampal Slices from Rats and Transgenic Mice for the Study of Synaptic Alterations during Aging and Amyloid Pathology
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Preparation of Acute Hippocampal Slices from Rats and Transgenic Mice for the Study of Synaptic Alterations during Aging and Amyloid Pathology

Published on: March 23, 2011

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在受伤的老哺乳动物皮层中,轴突再生受损和突触动力学增强

Cher Bass1,2,3, Anil A Bharath2, Vincenzo De Paola3,4,5

  • 1Centre for Neurotechnology, Imperial College London, London SW7 2AZ, UK.

iScience
|November 17, 2025
PubMed
概括

衰老会损害大脑的修复,减少轴突再生,但增加突触周转率,以进行潜在的重新连接. 这表明老年大脑可能通过突触可塑性适应损伤,为神经修复机制提供了洞察力.

关键词:
细胞神经科学 细胞神经科学分子神经科学分子神经科学

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