假肢超大化的临床影响在自我扩张的内透导管大动脉置换中
Andrea Ruberti1,2,3, Giovanni Occhipinti1,2,3, Matias Mon Noboa4
1Department of Cardiology, Cardiovascular Institute, Hospital Clinic, Barcelona, Catalunya, Spain.
Structural heart : the journal of the Heart Team
|November 17, 2025
概括
在跨导管大动脉置换 (TAVR) 中,对自扩张的跨导管心脏 (THV) 进行最佳尺寸定位至关重要. 较低的超大尺寸 (≤14%) 改善了TAVR患者的技术成功和减少了并发症.
科学领域:
- 心脏病学 心脏病学
- 干预心脏病学 干预心脏病学
- 医疗器械 医疗器械
背景情况:
- 准确的门尺寸对于成功的跨导管大动脉置换 (TAVR) 和跨导管心脏门 (THV) 的长期耐用性至关重要.
- 对于自我扩展 (SE) 的年内THV的最佳尺寸策略仍然是积极调查的领域.
研究的目的:
- 评估假肢超大尺寸对接受TAVR的患者手术和临床结果的影响.
- 具体评估Portico和Navitor SE年度内THV的结果.
主要方法:
- 400名接受TAVR的患者与SE年内THV进行了回顾性多中心研究 (2017年10月至2024年9月).
- 根据中位数 (14%) 的超大小,患者被分为低 (≤14%) 和高 (>14%) 的超大小组.
- 主要终点:技术成功;次要终点:30天设备成功,心脏起器植入,死亡率,住院,门功能障碍.
主要成果:
- 在低超大化群体中,技术成功率更高 (96.7%对92.1%,p=0.048).
- 栓栓塞仅发生在高超大小组 (2.1%,p=0.035) 中.
- 两组之间30天设备的成功率,膜回率或心脏起器植入率没有显著差异.
结论:
- 在TAVR与SE年内THV的低超大小 (≤14%) 与更好的技术成功有关.
- 这一策略还与减少门相关并发症,如栓塞等相关.
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