精确辐射瘤学的创新方法:先进的成像技术和挑战塑造了辐射治疗的未来
Yue Yan1,2,3, Daniel A Alexander1,2, Bryan P Bednarz4
1Department of Radiation Oncology & Applied Sciences, Dartmouth-Hitchcock Medical Center, Lebanon, NH, United States.
Frontiers in medicine
|November 17, 2025
概括
辐射瘤学中的精准医学正在推进新的成像技术,用于个性化癌症治疗. 实现充分的潜力需要验证,质量保证和公平的获取.
科学领域:
- 辐射疗法 辐射疗法
- 医疗成像医学成像
- 在瘤学瘤学.
背景情况:
- 放射性瘤学正在向精准医学转变.
- 影像学的进步使得个性化和适应性癌症治疗成为可能.
研究的目的:
- 审查新兴的成像指导放射治疗方法.
- 综合物理原理,应用,挑战和质量保证.
主要方法:
- 关于磁共振导向放射治疗,PET导向平台,先进的CBCT,切伦科夫成像,立体导向的综述.
- 检查质子疗法的创新 (DECT,pCT,体内范围验证).
- 探索量化成像在theranostics用于剂量测量.
主要成果:
- 新兴技术使得适应性,生物知情的剂量递送成为可能.
- 关键的创新包括MRgRT,PET引导,AI增强的CBCT和新型质子疗法验证方法.
结论:
- 充分的临床潜力需要多中心验证,标准化质量保证,多omics集成和可靠的自动化.
- 公平的准入,劳动力培训和可互操作的数据管道对于实施至关重要.
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