激烈的GABABR抑制了GLP-1RA的慢性作用,并减少心肌梗塞后心律失常的发生

Run Qi1,2,3, Zhang Jingjing4,5,6, Gu Hongchang1,2

  • 1Department of Cardiology, Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science, Xiangyang, Hubei, China.

Frontiers in pharmacology
|November 17, 2025
PubMed
概括

类似葡萄糖-1受体激动剂 (GLP-1RAs) 通过涉及GABAB受体的心脏自主机制影响心律. GABABR激活可以抵消GLP-1RA心律不良,但可以增强心肌梗塞后的抗心律不良作用.

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