相关实验视频
Updated: Apr 29, 2026

08:37
Corneal Donor Tissue Preparation for Endothelial Keratoplasty
Published on: June 12, 2012
28.2K
前腔炎症和脱膜内皮皮质角质形成术:以前部段OCT为基础的分析
Sabrina Vaccaro1, Giacomo Beschi2, Paola Cannistrà2
1Eye Unit, Azienda Socio Sanitaria Territoriale (ASST) Spedali Civili di Brescia, Brescia, Italia.
Ophthalmology science
|November 17, 2025
概括
前部段-OCT在Descemet膜内皮角质形成术 (DMEK) 后非侵入性检测亚临床炎症. 炎症标志物增加与早期术后并发症的风险更高相关,例如后侧纹和重新泡.
科学领域:
- 眼科医生 眼科 眼科
- 角膜外科手术 角膜外科手术
- 炎症成像 炎症成像
背景情况:
- 德塞梅特膜内皮皮质角膜整形术 (DMEK) 是一种用于角膜内皮功能障碍的手术程序.
- 评估DMEK后的亚临床炎症对于管理患者的治疗结果至关重要.
- 对于监测术后炎症,最好采用非侵入性方法.
研究的目的:
- 评估前段光学一致性断层扫描 (AS-OCT) 在检测亚临床前腔 (AC) 炎症方面的实用性.
- 在接受DMEK手术的患者中评估炎症标志物.
- 为了比较DMEK患者的炎症水平与健康的对照组.
主要方法:
- 在DMEK后对83只眼睛和15只健康的对照眼睛进行了回顾性分析.
- 使用AS-OCT对交流电池 (超反射点) 和火焰 (水相对空气相对强度[ARI]指数) 的量化.
- 在手术前和DMEK后1周,1个月,3个月的测量.
主要成果:
- 基线ARI指数在DMEK组比对照组高;AC细胞数量相似.
- 手术后的AC细胞数和ARI指数显著增加,在1周达到峰值.
- 在1周内增加的ARI显示与后侧侧膜 (PSRs) 有很弱的关联,而PSR与重新泡的需要有很强的相关性.
结论:
- AS-OCT提供了一种非侵入性方法,用于识别DMEK后的亚临床炎症.
- 在DMEK后炎症标志物升高可能表明早期术后并发症的风险增加.
- 非侵入性监测炎症可以帮助预测和管理潜在的并发症.
相关概念视频
Glaucoma: Overview
1.7K
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
1.7K
Angle Closure Glaucoma: Treatment
1.6K
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
1.6K

