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治疗复发性结直肠腺瘤与内镜粘膜切除

Stephanie Bou-Anak¹, Muhammad Khan², Ashlie Rubrecht³

¹Department of Pediatrics Akron Children's Hospital Akron Ohio USA.

|November 17, 2025

概括

一名患有腹痛的年轻男性患有难以切除的结肠多. 内镜粘膜切除 (EMR) 成功切除了腺瘤多,防止复发.

科学领域:

胃肠病学胃肠病学
结肠直肠手术结肠直肠手术
在瘤学瘤学.

背景情况:

结肠直肠多可能在年轻患者中呈现异常.
反抗性多体带来了管理方面的挑战.
家庭恶性瘤病史需要进行彻底的调查.

研究的目的:

报告一个单独的腺瘤结肠多的病例,通过内镜粘膜切除 (EMR) 进行管理.
突出管理青少年反抗性息肉的挑战.
讨论遗传因素在早期发病的息肉中的潜在作用.

主要方法:

一个17岁的男性患有腹痛,血和贫血的病例报告.
诊断工作包括上部内镜和结肠镜.
通过陷多角切除术和随后的EMR来管理单一的直指性腺瘤多.
遗传性结肠直肠癌遗传检测. 遗传性结肠直肠癌遗传检测. 遗传性结肠直肠癌遗传检测. 遗传性结肠直肠癌遗传检测. 遗传性结肠直肠癌遗传检测.

主要成果:

一个单独的,低度的失塑性腺瘤多被确定在rectosigmoid.
最初的陷多角切除术由于多重生而没有成功.
内镜粘膜切除 (EMR) 实现了全息肉切除.
基因检测显示RNF43基因中的VUS.
随访内镜检查显示,多没有复发.

结论:

EMR是一种治疗复发性腺瘤结肠多的有效方法.
青少年结肠多,即使是单独的,也需要彻底评估.
RNF43变异可能与早期发作的结直肠瘤有关.
密切的内镜监测在多切除后至关重要.

关键词:

结肠多重体的多重体.有关RNF43基因的研究.腺瘤多胞体的多胞体

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